Prostate cancer is metastatic if it has spread to these areas: Cancer spread may be seen on imaging studies and may show the cancer has spread. Metastatic Prostate CancerĬancer cells have spread beyond the prostate.

Imaging tests do not show signs the cancer has spread. This is found by a rise in the PSA level, while the testosterone level stays low. Prostate cancer that no longer responds to hormone treatment and is only found in the prostate. Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC) If this happens, the prostate cancer is considered CRPC. If the cancer cells begin to 'outsmart' hormone treatment, they can grow even without testosterone.

Typically, prostate cancer growth slows down with hormone therapy, at least for some time. That fuel includes male hormones or androgens (like testosterone). It is given through medicine or surgery to most men with prostate cancer to reduce the testosterone “fuel” that makes this cancer grow. Hormone therapy is also called testosterone depleting therapy or androgen deprivation treatment (ADT) and can help lower your natural testosterone level. CRPC means the prostate cancer is growing or spreading even though testosterone levels are low from hormone therapy. Castration-Resistant Prostate Cancer (CRPC)Ĭastration-resistant prostate cancer (CRPC) is a form of advanced prostate cancer. With biochemical recurrence, the prostate-specific antigen (PSA) level has risen after treatment(s) using surgery or radiation, with no other sign of cancer. There are several types of advanced prostate cancer, including: Biochemical Recurrence Treatment can help slow advanced prostate cancer progression. Advanced prostate cancer is not “curable,” but there are many ways to treat it. When an early stage prostate cancer is found, it may be treated or placed on surveillance (watching closely). Advanced | Stage IV: Cancer has spread outside the prostate to other parts such as the lymph nodes, bones, liver or lungs.Locally Advanced | Stage III: Cancer has spread outside the prostate but only to nearby tissues.Early Stage | Stages I & II: The tumor has not spread beyond the prostate.Prostate cancer is often grouped into four stages, with stages III and IV being more advanced prostate cancer. When prostate cancer spreads beyond the prostate or returns after treatment, it is often called advanced prostate cancer.

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